Smallpox – 100 Times Deadlier Than COVID-19: The Brutal History and the Controversial Origin of Vaccines

(بسم الله الرحمن الرحيم، والصلاة والسلام على حبيبنا محمد صلى الله عليه وسلم وعلى من اتبع صراطه المستقيم.) In the name of Allah (سبحانه وتعالى)- the Most Merciful. May peace and blessings be upon our beloved Prophet Muhammad (ﷺ) and upon all those who follow his righteous path. 

Dear Readers, 

(السلام عليكم ورحمة الله وبركاته.) May Peace, Mercy, and Blessings of Allah be upon you. 

While the world was recently brought to a standstill by the COVID-19 pandemic, history reminds us of a far more sinister shadow that haunted humanity for over 3,000 years: smallpox. With a staggering 30% fatality rate, it claimed over 500 million lives in the 20th century alone. This isn't just a medical history; it’s a gripping saga of scientific audacity, ethical dilemmas, and a triumph over deep-rooted superstitions. If you want to understand how a farm animal and a life-risking experiment on a child saved civilization—and why this "extinct" virus is still guarded in high-security labs today—this deep dive is for you.

A split-screen digital art showing Dr. Edward Jenner vaccinating a boy in 1796 and a modern scientist in a biohazard suit holding a Smallpox virus sample.

                  Table of Contents:

  • The Scale of Terror: Why Smallpox Dwarfs Modern Pandemics.
  • The "Speckled Monster": A Disease That Redefined Suffering.
  • The Rural Secret: The Milkmaid’s Observation.
  • A Controversial Breakthrough: Dr. Jenner and the First Subject.
  • Global Resistance: From Cow-Headed Myths to Modern Anti-Vax.
  • The Final Victory: The Only Human Disease Ever Eradicated.
  • FAQ: Addressing Modern Concerns.

1. The Scale of Terror: COVID-19 vs. Smallpox:

To put things into perspective, the global mortality rate for COVID-19 hovered around 1%. In contrast, smallpox killed 1 out of every 3 people it infected. While COVID-19 primarily affected the respiratory system, smallpox was a systemic assault, often leaving survivors blind or permanently disfigured. It remains the deadliest enemy humanity has ever faced.

2. The "Speckled Monster": 500 Million Deaths:

Known as the "Red Plague", smallpox ravaged empires and decimated populations. Spread through the air and contaminated surfaces, the Variola virus turned the skin into a mass of painful, fluid-filled pustules. In the 20th century alone, before its eradication, it killed more people than both World Wars combined.

3. The Rural Secret: The Milkmaid’s Observation:

In the late 1700s, a fascinating piece of folklore circulated in rural England. Dairymaids claimed they were immune to smallpox because they had previously contracted "cowpox"—a much milder disease caught from cows. This local observation became the catalyst for the greatest medical breakthrough in history.

4. A Controversial Breakthrough - Dr. Jenner and James Phipps:

In 1796, Dr. Edward Jenner decided to test this folklore. His method, however, would be considered a major ethical violation today:

He inoculated James Phipps, an 8-year-old boy, with pus from a cowpox lesion.
After the boy recovered from a mild fever, Jenner intentionally exposed him to the deadly smallpox virus multiple times to check for immunity.

The Result: The boy remained healthy. The world’s first vaccine was born. The term "Vaccine" originates from the Latin Vacca, meaning "Cow."

5. Global Resistance- From Cow-Headed Myths to Modern Anti-Vax:

Human nature remains consistent across centuries. When Jenner’s vaccine was introduced, it met fierce resistance. Satirical cartoons of the era depicted people sprouting cow heads after vaccination, and religious leaders argued that interfering with a "divine disease" was a sin.

6. The Final Victory- Eradication and the Modern Risk:

In 1979, the World Health Organization (WHO) declared smallpox officially eradicated—the only human disease to achieve this status. Today, living samples are still stored in two high-security labs: the CDC in the USA and the VECTOR Institute in Russia. While kept for research, they represent a lingering biological wildcard.

7. Frequently Asked Questions (FAQ):


Q1: Was Smallpox really 100 times deadlier than COVID-19? 
Statistically, yes. With a 30% mortality rate and a much higher incidence of permanent disability, its impact on the global social fabric was far more devastating than modern respiratory viruses.

Q2: How does smallpox differ from chickenpox? 
They are entirely different viruses. Chickenpox is caused by the Varicella-zoster virus and is rarely fatal, whereas Smallpox was caused by the Variola virus and was a catastrophic systemic disease.

Q3: What is the circular scar on the arms of older generations? 
If you see a distinct round scar on the upper arm of someone born before 1980, it is likely from the Smallpox vaccine. The "bifurcated needle" used for vaccination created a small lesion that left a permanent mark.

Q4: Is the vaccine still required today? 
No. Routine vaccination for the general public ended in the late 1970s.

Q5: Can smallpox ever return? 
Theoretically, only through a laboratory accident or intentional misuse of stored samples. Global health organizations maintain strict surveillance to prevent such a scenario.

We Want to Hear From You!

Do you or your family members still carry the Smallpox vaccine scar?

In an era of biosecurity risks, do you believe the remaining samples of the virus should be destroyed or kept for research?

Share this article with your network to spread awareness of this incredible human victory. Drop your thoughts in the comments below!

#MedicalHistory, #SmallpoxVsCovid19, #VaccineOrigin, #GlobalHealth, #ScienceHistory,  #HumanVictory, #Biosecurity



Thank you for taking the time to read this inspiring story. We hope it has uplifted and motivated you to overcome any challenges you may be facing. "The best among you is the one who benefits others." (Musnad Ahmad, Hadith: 22803). If you found this information helpful, like💙 , upvote ✅, clap 🙏🏼, comment 💯, and share 📩 your thoughts or experiences in the comments below. Your engagement helps spread awareness and keeps our community informed and motivated. Let’s achieve our goals together! Disclaimer: This blog post is for informational purposes only and does not constitute professional advice. It is important to seek help from a qualified professional. 

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